What is Fluoxetine: How to use, Side Effects, Dosage

What is Fluoxetine: How to use, Side Effects, Dosage

What is Fluoxetine

Fluoxetine affects the brain chemicals that may be unbalanced in people with depression, panic, anxiety, or obsessive-compulsive symptoms. Fluoxetine is a selective serotonin reuptake inhibitor (SSRI).

Fluoxetine is sometimes used with another drug called olanzapine (Zyprexa) to treat bipolar manic depression. This compound has also been tested for depression after at least 2 other drugs without successful treatment of symptoms.

Fluoxetine is used to treat depression, biological nervous system (eating disorder), obsessive-compulsive disorder, panic disorder, and premenstrual dysfunction (PMDD).

PROZAC® (fluoxetine capsules, USP) is a selective serotonin reuptake inhibitor for oral administration. It is also marketed for the treatment of premenstrual dysphoric disorder (Sarafem®, fluoxetine hydrochloride). It is designated (±)-Nmethyl-3-phenyl-3-[(α, α,α-trifluoro-p-tolyl)oxy]propylamine hydrochloride and has the empirical formula of C17H18F3NO•HCl. Its molecular weight is 345.79. (read full information about prozac: What is Prozac?)

Fluoxetine Hydrochloride is a white to white crystalline solid that dissolves in water at 14 mg / ml.Each Pulvule contains fluoxetine hydrochloride equivalent to 10 mg (32.3 μmol), 20 mg (64.7 mmol) or 40 mg (129.3 μmol) of fluoxetine. Pulvules also contain starch, gelatin, silicon, titanium dioxide, iron oxide and other inactive ingredients. Pulvules 10 and 20 mg Also contains FD & C Blue No 1 and 40 mm Pulvule also contains FD & C Blue No. 1 & FD & C Yellow No. 6 are.

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How to use Fluoxetine

Take the liquid medicine with a syringe dose, or with a special spoon for a dose or medicine cup. If you do not have a dose measuring device, ask your pharmacist for one.

Do not open the lag, chew, break or open the capsule. Swallow it all.

To treat prenatal panic disorder, the usual dose of fluoxetine is once a day while you have your course, or 14 days before you start your course. Follow your doctor's instructions.

It may take 4 weeks to improve your symptoms. If your symptoms do not heal, take medication and tell your doctor.

Do not stop fluoxetine suddenly or while you have unpleasant withdrawal symptoms. Ask your doctor how to stop fluoxetine safely.

Put this medicine in your doctor's mouth, usually once in the morning. If you take this medicine twice a day.

If you take fluoxetine for premenstrual problems, your doctor may refer you to your daily full day of the month or just 2 weeks before your term. To help you remember, check your calendar.

If you use this form of liquid, measure the dose accurately using a measuring device / spoon. Do not use a spoon because you may not have a proper dose.

Dosage of Fluoxetine

Depression in adults is treated with 20-80 mg of fluoxetine daily. The recommended dose for treating depression in children is 10-20 mg daily. After 13 weeks of daily administration, 90 mg once weekly may be effective in some patients.

Symptoms of overdose

Animal experience

Animal studies do not provide accurate, or necessarily valid, information on the treatment of human abuse. However, animal testing can provide useful insights on possible treatment strategies.

The mean mortality rate in mice was 452 and 248 mg / kg, respectively. Acute high oral doses increase over-tolerability and seizure in several animal species.

In a single dose study, ECG does not show long-term dogs with PR, QRS, or QT courses. Tachycardia and hypertension. As a result, ECG levels are unknown in the prediction of cardiac toxicity. However, the ECG should normally be considered in cases of over-human obstruction (see Management overdose).

Manage overdose

For current information on over professional management, contact a testing center for poison control (1-800222-1222 or www.poison.org). Treatment should be one of the general measures taken to manage excessive drug use. Consider the possibility of reopening too many medications.

Ensure air, oxygen and ventilation. Monitor heart rhythm and vital signs. Use supportive and wise measures. Induction of nausea and vomiting is not recommended.

Activated charcoal should be prescribed. Due to the large volume of distribution of this drug, compulsive diuresis, dialysis, hemophuroph and the exchange of rheumatoid arthritis is unlikely to be beneficial. No specific antibodies to fluoxetine have been identified.

A special alert includes consuming patients or has recently taken fluoxetine and consumes excess amounts of TCA. In such cases, the accumulation of tertiary calcium and / or active metabolite may increase significantly clinical complications and increase the time required for close medical observation (see Interactions of Drugs).

For specific information on combining overdosage with olanzapine and fluoxetine, refer to the Overdosage Symbyax package insert.

Human experience

Worldwide exposure to fluoxetine hydrochloride is estimated to be more than 38 million patients (around 1999). Of the 1,578 over-the-counter uses of fluoxetine hydrochloride alone, or with other drugs, the reported population was 195 deaths.

Of the 633 adult patients taking alone excessive fluoxetine hydrochloride alone, 34 cases of sudden death, 378 fully recovered, and 15 patients after administration, including abnormal side effects, abnormal walking, confusion, lack of response, concern, Pulmonary dysfunction, dizziness, tremor, high blood pressure, impotence, motor disorder, and hypomagia. The remaining 206 patients had unknown results. The most common symptoms and symptoms associated with unexpected overdosage were seizure, drowsiness, nausea, tachycardia and vomiting. The largest known use of fluoxetine hydrochloride in adults was 8 g in the patient who left fluoxetine and then recovered. However, in an adult patient who left fluoxetine, over 520 mg was associated with fatal outcome, but the cause has not yet been proven.

Among children between the ages of 3 and 17, there were 156 excessive fluoxetine alone or in combination with other drugs. Six patients died, 127 patients recovered completely, 1 patient experienced renal failure, and 22 had unknown results. One of six deaths was a 9year old boy with a history of OCD, Tourette with tics syndrome, attention deficit disorder, and fetal alcohol syndrome. He received daily fluoxetine 100 mg daily for 6 months in addition to clonidine, methylphenidate and promethazine. The use of mixed medications or other suicide attempts, all 6 times in children, results in death. The biggest consumption in children was 3 g, which was non-gum.

Other important side effects reported with excessive intake of fluoxetine (single or multiple drugs) include coma, delirium, ECG disorders (such as nodal rhythm, QT interval, and ventricular arrhythmias, including Torsades de Pointes arrhythmias), Blood Pressure, Mania, Neuroleptic Malignant Syndromes, Similar Reactions, Periclase, Aspure and Syncope.


Please if you have any questions about Fluoxetine, you can ask us by commenting below this text, we'll answer you as soon as possible.

Side effects of Fluoxetine

Report any new symptoms or worsening to your doctor, such as: mood or behavioral changes, anxiety, panic attacks, drowsiness, or if you feel irritable, irritable, disturbed, hostile, aggressive, restless, Have too much (mentally or physically) depression, or have your thoughts about suicide or harm yourself.

In the case that:

Dark vision, tunnel vision, eye pain or swelling, or viewing aura around the lights;

High level of serotonin in the body - Stimulation, hallucinations, fever, heart rate, overactive hypertension, nausea, vomiting, diarrhea, loss of coordination, fainting;

Low levels of sodium in the body - Headache, confusion, boredom, severe weakness, vomiting, loss of coordination, feeling insecure;

Severe nervous system reaction - very stiff (rigid) muscles, high fever, sweating, confusion, rapid or uneven heartbeat, tremor, feeling like you may be lost; or

Severe skin reaction - fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, then a red or purple skin rash that spreads especially in the face or body and causes flaking and the skin. Vectorized.

Common side effects of fluoxetine may include:

Sleep problems (insomnia), strange dreams;

Headache, dizziness, vision changes;

Trembling or shaking, feeling anxious or nervous;

Pain, weakness, yawning, feeling tired;

Stomach upset, loss of appetite, nausea, vomiting, and diarrhea;

Dry mouth, sweating, flushing;

Change in weight or appetite;

Painful nose, sinus pain, sore throat, flu symptoms; or

Decreased libido, impotence, or having an orgasm problem.

This list is not the full list of side effects and others may occur.

The undesirable reactions that may occur are listed below:

BOX WARNING AND WARNINGS AND PREVENTION Children and adolescents suicidal thoughts and behaviors

Serotonin Syndrome

Allergic and rash reactions

Screening for patients with bipolar disorder and control of mania / hypomagia Seizures

Appetite and weight changed

Abnormal bleeding

Closed-angle glaucoma


Anxiety and Insomnia

Duration QT

Potential for cognitive and motor disorder

Unwanted reactions interrupted

Drugs that may interact with Fluoxetine

Taking fluoxetine with other medicines that cause drowsiness or slow breathing can cause serious side effects or death. Ask your doctor for advice before taking a sleep pill, pain medication, and cough medication, relaxation of the muscle or medication for anxiety, depression or seizure.

Many drugs can interact with fluoxetine. All possible interactions are not listed here. Tell your doctor about all your current drugs and start and stop everything, especially:

Any other type of antidepressant

Saint John's yeast;

Tryptophan (sometimes called L-Tryptophan);

Blood Drinks - Warfarin, Coumadine, Yanoton;

Medication to treat anxiety, mood disorders, mental disorders, or mental illness - amitriptyline, asperin, dysapamine, lithium, neuritis, and many more.

Medication for the treatment of ADHD or narcolepsy - Adderall, Concerta, Ritalin, Vyvansse, Zenzedi and others;

Migraine headaches - Rosa Tryptane, Suprepitane, Zolmeteraptan and others. Or

Antipyretic drug - Fentanyl, Tramadol.

This list is not complete and many other drugs can be contacted with fluoxetine.

For whom Fluoxetine might not be safe

Do not use fluoxetine, if over the past 14 days, you have used an MAO inhibitor. Dangerous drug interactions may occur. MAO inhibitors include isoccarbazole, linzolide, phenolsin, razgelin, sulginin and tanylcypromine. You must wait at least 14 days after stopping MAO inhibitor before taking fluoxetine. You must wait 5 weeks after stopping fluoxetine before taking thrididine or an MAOI.

Tell your doctor about all other antidepressants you specially Celexa, Cymbalta, Desyrel, Effexor, Lexapro, Luvox, Oleptro, Paxil, Pexeva, Symbyax, Viibryd or Zoloft.

If you are allergic to it, you should not use fluoxetine, if you take pimoside or tryididine, or if you are being treated with methylen blue.

Some drugs can interact with fluoxetine and cause serious illness called serotonin syndrome. Make sure your doctor knows about all the other medications you use. Ask your doctor before any change in the way your medicine is used.

Tell your doctor if you are sure that fluoxetine is safe for you.

Cirrhosis of the liver;

Kidney disease;


Angular glaucoma;

Seizure or epilepsy;

Bipolar disorder (manic depression);

History of drug use or suicidal ideation; or

Fluoxetine is not approved for use by anyone younger than 18 years old.

2-Do not use fluoxetine if you:

Allergies to fluoxetine hydrochloride or any of the ingredients in PROZAC. End of this medication guide for the full list of ingredients in PROZAC.

Take a monoamine oxidase inhibitor (MAOI). Ask your healthcare professional if you are not certain if you are taking a MAOI, including antibiotic linidolysid.

Do not take MAOI within 5 weeks of stopping PROZAC unless your doctor does this.

Can you use Fluoxetine while pregnancy?

Using anti-depressant drugs during pregnancy may cause serious lung problems or other complications in the baby. However, if you are taking antidepressants, you may experience a recurrence of depression.

If you are pregnant, tell your doctor immediately. Do not start taking or stopping fluoxetine during pregnancy without consulting your doctor.

During pregnancy, this medication should only be used when needed. It may be harmed to a baby. Also, babies born to mothers who have taken the drug for the last 3 months of pregnancy can rarely develop symptoms such as nourishment / respiration, seizure, muscle stiffness or permanent crying. If you notice any of these symptoms in your baby, tell your doctor immediately.

Warnings of Fluoxetine

This medicine may cause dizziness or drowsiness. Alcohol or marijuana can cause your dizziness or sleepiness.

Fluoxetine may cause a condition that affects your heart rhythm (QT prolongation). The duration of QT can rarely lead to serious / rash, and other symptoms (such as severe dizziness, choking), which can rarely lead to medical attention soon. Do not drive, use machines, or do anything that you need to be alert to as long as you can safely do it. Avoid alcoholic beverages. Talk to your doctor if you use marijuana.


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