What is Flexeril: Side Effects, How to use, dosage

What is Flexeril: Side Effects, How to use, dosage

What is Flexeril

Flexeril is used with rest and physiotherapy to treat skeletal muscle, such as pain and damage.

Flexeril (cyclobenzaprine) is a sedative muscle. It works by blocking the nerve (or pain sensation) that is sent to your brain.

Cyclobenzaprine hydrochloride is a white, crystalline tricyclic amine salt with the empirical formula C20H21N•HCl and a molecular weight of 311.9. If aqueous solutions are made alkaline, the free base separates. It has a melting point of 217°C, and a pKa of 8.47 at 25°C. It is freely soluble in water and alcohol, sparingly soluble in isopropanol, and insoluble in hydrocarbon solvents. Cyclobenzaprine HCl is designated chemically as 3-(5H-dibenzo [a,d] cyclohepten-5-ylidene)-N, Ndimethyl- 1-propanamine hydrochloride

FLEXERIL 5 mg (Cyclobenzaprine HCl) is supplied as a 5 mg tablet for oral administration. Flexeril 10 mg (cyclobenzaprine HCl) is supplied as a 10 mg tablet for oral administration.

FLEXERIL tablets contain inactive ingredients: hydroxypropylcellulose, hydroxypropylmethyl cellulose, iron oxide, lactose, magnesium stearate, starch and titanium dioxide. The 5 mg FLEXERIL tablet also contains yellow D & C # 10 aluminum lake HT and yellow FD & C # 6 Aluminum Lake.

Please if you have any questions about Flexeril, you can ask us by commenting below this text, we'll answer you as soon as possible.

How to use Flexeril

Take this medicine with a glass of water.

Flexeril is only part of a complete treatment program that may include rest, physiotherapy or other pain relief measures. Follow your doctor's instructions.

Dosage of Flexeril

FLEXERIL tablets are available in 5 mg and 10 mg doses. 5 mm tablet of yellow and orange tablets, 5-way, and pills covered with drug tablets, FLEX has encoded more than 5 digits on one side and without coding on the other. 10 mm yellow, double-sided D-shaped tablets, film-coated tablets, coded FLEXERIL on one side and no planning on the other. The two doses are:

5 mg 100 NDC counters 50458-280-10

10 mg 100 bottles of NDC 50458-874-11

Symptoms of overdose

1-Signs of overdose may include drowsiness, rapid heartbeat, tremor or shaking, mild reaction, confusion, nausea, vomiting, hallucinations (seeing things), chest pain or seizure.

2-Although rare, deaths may occur through overdosage with FLEXERIL. The use of multiple drugs (including alcohol) in excessive intake of cyclo-blansuprin is intentional. Given that overdecular management is complex and changing, it is recommended that the doctor contact a venom control center for information on treatment. Symptoms and signs of toxicity may increase rapidly with cyclenoencephrine, so hospital monitoring is needed as soon as possible. The oral LD50 of Flexiril is 338 and 425 mg / kg, respectively, in mice and mice respectively.

Side effects of Flexeril

Get medical help if you have any of these symptoms: hives; difficulty breathing, swelling of the face, lips, tongue or throat.

If any of these serious side effects occur, stop using Flexeril and contact your doctor.

Fast, palpitations or heartbeats;

Chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general feeling of being unwell;

Sudden insomnia or weakness, especially on one side of the body;

Sudden headache, confusion, vision problems, speech or balance;

Feeling dizzy, faint;

Confusion, weakness, lack of coordination;

Nausea, stomach ache, low fever, loss of appetite, dark urine, gray stool, jaundice (yellowish skin or eyes);


Abnormal thoughts or behaviors, illusion (seeing things); or

Bruises or bleeding easily, unusual weakness.

Rare side effects of Flexiril may include:

Dry mouth or throat;

Blurred vision;

Drowsiness, dizziness, feeling tired;

Loss of appetite, stomachache, nausea

Diarrhea, constipation, gas; or

Muscle weakness.

This list is not full list of side effects and others may occur.

The following adverse reactions have been reported in post marketing experience or less than 1% of patients in clinical trials with a 10 mg tablet:

Body as a whole: Syncope; Weakness

Cardiovascular system: Tachycardia; Arrhythmia; Vaginal divorce; Hypotension

Digestion: vomiting; anorexia; diarrhea; gastritis; stomach pain; thirst; flatulence; abdominal pain; abnormal liver function; rare reports of hepatitis, jaundice and cholestasis.

Increased sensitivity: anaphylaxis; angioedema; itching; facial rash; rash; rash.

Musculoskeletal: Local weakness.

Neuropsychiatric system: Seizure, Ataxia; Vertigo; Dyspareunia; Hypertonia; Muscle skeletal metabolism; Degradation; Insomnia; Depression; Abnormal feelings; Anxiety; Stimulation; Psychosis; Abnormal Thinking and Dream; Thriller; Paresthesia Diallopia

Skin: sweating.

Special symptoms: Nervous; tinnitus

Urogenital: Frequency of urination and / or retention.

Relationship unknown cause

Other reactions that are rarely reported for FLEXERIL, in the absence of a causal relationship for other triple-drug therapies, can be addressed as warning information for physicians:

Body as a whole: Chest pain; Edema

Cardiovascular system: high blood pressure; myocardial infarction; heart block; stroke;

Gastrointestinal paralysis, discoloration of the tongue; stomatitis; parotid swelling

Endocrine: Inappropriate ADH syndrome

Hemach and Lymph: Purpura; Bone marrow depression; Leukopenia; Eosinophilia; Thrombocytopenia.

Metabolic, Nutrition and Safety: Increases and decreases in blood glucose, weight gain or weight loss.

Skeletal muscle: Mayalgi.

Neuropsychiatric system: Reduced or increased libido; abnormal walking; illusions; violent behavior; paranoid; peripheral neuropathy; Bell's paralysis; changes in EEG patterns; extrapyramidal symptoms.

Breathing: shortness of breath.

Skin: Sensitivity to light; Alopecia

Urine: urinary incontinence; urinary tract obstruction; impotence; testicular swelling; gynecomastia; breast enlargement; galactorrhea

Substance abuse and dependence.


Please if you have any questions about Flexeril, you can ask us by commenting below this text, we'll answer you as soon as possible.

Drugs that may interact with Flexeril

Many medications can interact with Flexeril. Below is just a small list. If you are using any drug of this list, tell your doctor:

Atropine (Donatal and others), benzodopinin (Cogentin), dimenhydrinate (methisopalamine (pamine) or scopolamine (Transderm-Scop);

Glycopyrrolate (robinol);

A bronchodilator such as Ipratroprium (Atrovent) or Tiotropium (Spiriva);

Guanethidine (Iselin);

Tramadol (Ultram);

Mappensolate (Kantile);

Bladder or urinary drugs such as Darphanacin (Enablex), Fluvoxate (Urispas), Oxybutynin (Dipropran, Oxytrol), Tolerodine (Detroth) or Celifenacin (Vesicare); or

Irritable bowel drugs such as dicyklomin (benzyl), hyoscyamine (Anaspaz, Cystospaz, Levsin and others) or Pro-Banthine.

This list is not complete and there may be other drugs that would interact with Flexeril. Tell your doctor about prescription drugs and over-the-counter prescription drugs, vitamins, minerals, herbal products, and other prescriptions prescribed by other doctors. Do not start new medications without talking to your doctor.

FLEXERIL may increase the effects of alcohol, barbiturates and other CNS depression.

Tricyclic antidepressants may increase the risk of seizures in patients taking tramadol.

Tricyclic antidepressants may prevent antihyperglycemia and similar compounds.

For whom Flexeril might not be safe

Elderly adults may be susceptible to the side effects of this drug, especially drowsiness, confusion, constipation or urination. Sleepiness and confusion can increase the risk of falling.

Can you use Flexeril while pregnancy?

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

Warnings of Flexeril

In short-term studies of non-muscle spasm symptoms associated with acute skeletal musculoskeletes and usually at higher doses than those recommended for skeletal muscle spasm, there are some serious reactions to the central nervous system that are associated with triple antidepressants

Cyclobenzaprine is close to the tricyclic antidepressants, including amitriptyline and imipramine.

Three-ring antidepressants have been reported to produce arrhythmia, sinus tachycardia, prolonged lead times to myocardial infarction and stroke.

This medicine may cause dizziness or drowsiness. Do not drive, use machines, or do anything that you need to be alert to as long as you can safely do it. Avoid alcoholic beverages. Talk to your doctor if you use marijuana.

Before your surgery, tell your doctor or dentist all the products you are using (including prescription drugs, over-the-counter prescriptions, and herbal products).

Keep all drugs away from children and pets. Store at room temperature away from light and moisture. Do not store in the bathroom.


Please if you have any questions about Flexeril, you can ask us by commenting below this text, we'll answer you as soon as possible.

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