What is Admelog: How to Use, Dosage, Side Effects

What is Admelog: How to Use, Dosage, Side Effects

What is Admelog

Admelog is used to improve blood glucose control in adults and children with diabetes. Admelog is used to treat type 2 diabetes in adults and type 1 diabetes in adults and children of at least 3 years of age. ADMELOG (insulin lispro injection) is a rapid-acting human insulin analog used to lower blood glucose. Insulin lispro is produced by recombinant DNA technology utilizing a non-pathogenic laboratory strain of Escherichia coli. Insulin lispro differs from human insulin in that the amino acid praline at position B28 is replaced by lysine and the lysine in position B29 is replaced by praline.

Insulin is a hormone that works by lowering the level of glucose (sugar) in the blood. Admelog is a fast acting insulin that starts working about 15 minutes after injection, the peak is about 1 hour, and lasts for 2 to 4 hours. Chemically, it is Lys(B28), Pro(B29) human insulin analog and has the empirical formula C257H383N65O77S6 and a molecular weight of 5808, both identical to that of human insulin.

Admelog may also be used for the purposes of this medication guide.

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How to use Admelog?

Admelog is injected under the skin or into the vein using an injection pump. A health care provider will teach you how to properly use your Admelog.

Use this medication within 15 minutes before or right after meals.

Admelog Concentration (200 units) should not be given with an insulin pump or mixed with other insulins.

Just prepare your injection when you are injected. If the drug does not change in terms of cloud, color or particles, do not use it. Read your pharmacist for a new drug.

Before injecting each dose, clean the injection site with rubbing alcohol. Change the injection site every time to reduce damage to the skin and prevent skin problems (lipodystrophy). Incremental insulin may be injected into the stomach, thigh, buttock or back of the arm. Do not inject the pill, swelling or itching into the skin. Do not inject the cold insulin because it can be painful. The insulin capacity you are currently using can be stored at room temperature. Do not inject if you have low blood sugar. Do not rub the area after injection.

Put this medicine under the skin under your doctor's injection, usually within 15 minutes before eating or immediately after a meal. Do not inject into the vein or muscle as your blood sugar (hypoglycemia) may be low. Because it is fast acting, just after taking an insulin dose, it may lead to a decrease in blood glucose.

Dosage of Admelog

Always check insulin labels before administration. Do NOT mix ADMELOG with other insulins when administering using a continuous subcutaneous infusion pump.

Inspect ADMELOG visually before use. It should appear clear and colorless. Do not use ADMELOG if particulate matter or coloration is seen.

Symptoms of over dose

Excessive consumption of insulin can lead to hypoglycemia at risk. Symptoms include drowsiness, confusion, numbness or burning in the mouth, blurred vision, difficulty speaking, muscle weakness, cramping movements, seizures, or loss of consciousness.

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Side Effects of Admelog

In the case that you feel any of the below effects, make sure you take the best medical care:

Weight gain, swelling in the hands or feet, feeling short of breath; or

Low potassium - leg cramps, constipation, irregular heartbeat, chest vibration, thirst or urination, stomach or burning sensation, muscle weakness or chills.

Common side effects may include:

Low blood glucose;

Itching, itchy skin; or

The thickening or wrinkling of the skin in which you have injected.

This list is not the full list of side effects and others may occur.

The following adverse reactions are also common:


Hypersensitivity and allergic reactions


Drugs that may interact with Admelog

Many other drugs can affect your blood glucose and some drugs can increase or decrease insulin's effects. Some medications can also cause fewer symptoms of hypoglycemia, which suggests that when your blood glucose is low, it gets harder. Tell each of your health care providers about all the medications you are currently using and stop taking any medication that you start using or using. This includes prescription and over-the-counter prescriptions, vitamins and herbal products.

Medicines That May Decrease the Blood Glucose Lowering Effect of ADMELOG

The glucose lowering effect of ADMELOG may be decreased when coadministered with corticosteroids, estrogens, isoniazid, niacin, oral contraceptives, phenothiazines, danazol, diuretics, sympathomimetic agents (e.g., epinephrine, albuterol, and terbutaline), somatropin, atypical antipsychotics, glucagon, protease inhibitors, and thyroid hormones.

Medicines That May Increase the Risk of Hypoglycemia

The risk of hypoglycemia associated with ADMELOG use may be increased when coadministered with antidiabetic agents, salicylates, sulfonamide antibiotics, monoamine oxidase inhibitors, fluoxetine, disopyramide, pramlintide, fibrates, propoxyphene, pentoxifylline, ACE inhibitors, angiotensin II receptor blocking agents, and somatostatin analogs (e.g., octreotide). Dose adjustment and increased frequency of glucose monitoring may be required when ADMELOG is coadministered with these drugs.

For whom Admelog might not be safe

You should not use Admelog if you are allergic to it or if you have a part of your hypoglycemia. Admelog should not be given to a child under the age of 3 years. It should not be used to treat type 2 diabetes in a child of any age.

If you have ever had, tell your doctor:

Liver or kidney disease; or

The levels of potassium in your blood (hypokalemia).

Tell your doctor if you are taking medicines containing pioglitazone or rosiglitazone. Taking some of the diabetic glucose drugs while you use insulin may increase the risk of serious heart problems.

Admelog Warnings

Never share pen, cartridge, or syringe with someone else, even if the needle has changed.

Unopened storage (not in use) Admelog:

Cool down and use until the expiration date; or

Store at room temperature and use for 28 days.

Control your blood glucose when your body is affected (such as fever, infection, damage, or surgery). Talk to your doctor, because your changes in your blood glucose, drug, or blood tests may change.

Before your surgery, tell your doctor or dentist all the products you are using (including prescription drugs, over-the-counter prescriptions, and herbal products).

Check your blood glucose before and after exercise. You may need a snack before.

Ask your doctor about how to adjust your insulin when traveling to time zones. Take extra insulin and avoid taking it.

Open storage (in use) Admelog:

Store the vial in a refrigerator or at room temperature and use it for 28 days.

Keep the cartridge or injection pen (no needle attached) at room temperature and use within 28 days.

Alcohol should be limited while using this medicine as it may increase the risk of hypoglycemic insufficiency.

Elderly adults may be more susceptible to side effects, especially low blood sugar.

Children may be more susceptible to side effects, especially low blood sugar.

If you are pregnant, tell your doctor immediately. Pregnancy may increase or increase diabetes. Plan your doctor to control your blood glucose during pregnancy. Your doctor may change your diabetes during pregnancy (such as diet and insulin therapy).

This medicine is for breast milk; it is unlikely to give milk to a breast milk. Consult your doctor before breast-feeding. Your insulin needs may change during breastfeeding.

If using this drug in an insulin pump, do not store this drug in the pump for more than 7 days. Doing so may lead to ineffective treatment and high blood sugar. Protect insulin from light and heat.  Do not expose the insulin in your pump to direct sunlight or temperatures above 98.6 degrees F (37 degrees C).

Do not keep it in the bathroom. Keep all medications away from children and pets.

Please if you have any questions about Admelog, you can contact us in comments and take our free recommendations

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