Heparin: How to use, Side Effects, Dosage

Heparin: How to use, Side Effects, Dosage

What is Heparin?

Heparin is an anticoagulant (a blood thinner) that blocks the formation of blood clots.

Heparin is used to treat and prevent blood clots by some medical conditions or medical procedures. Heparin is also used to reduce the risk of blood clotting before surgery.

Injection of Heparin Sodium, USP is a sterile and non-pare genetic solution of sodium heparin (derived from intestinal mucosal mucosa) in water for injection. Each container contains 10000, 12500, 20000 or 25000 units of USP heparin; 40 or 80 mg sodium chloride added to add isotonic (see sections for different sizes and strengths). It may contain sodium hydroxide and / or hydrochloric acid to adjust ph. pH 6.0 (5.0 to 7.5).

This drug is free to maintain IV catheter. Heparin helps to smooth blood flow and works better by clotting the catheter by creating a specific natural substance (anti-clotting protein). It is an anticoagulant known.

This form of heparin should not be used to treat or prevent blood clotting in the body.

Some products should not be used for infants due to increased risk of side effects. Check with your doctor or pharmacist for details.

This solution does not contain any bacteriostatic, antimicrobial agent or buffer and is only used to inject a dose. When smaller doses are needed, the unused portion should be eliminated.

Sodium heparin is in the ADD-Vantage ™ system for intravenous infusion only after dilution.

Do not use heparin for intravenous catheter (IV) catheterization. A separate heparin product is available for use as a catheter valve closure. Using the wrong type of heparin for catheter drainage can lead to lethal bleeding.

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How to use Heparin?

Do not use the drug if the color is changed or particles are in it. Ask your pharmacist for a new drug.

You may be injected from injected heparin to an oral mouth (mouth). Stop using heparin until your doctor tells you. You may need to use an injection and oral forms of heparin for a short time.

This medicine is given by your doctor by injection into IV catheter. Do not inject this medicine into the body.

Heparin is in many strengths. When using the wrong power, severe damage (sometimes death) has occurred. Use proper strength and dose before using this medicine.

Place the catheter / line with normal saline before and after injection of heparin-like drugs such as Suspan, Dopropoidine, Cyproloxacin and Mitoxantrone.

Heparin increases the risk of your bleeding, which can be severe or life-threatening. You will need repeated tests to measure the time of blood clotting. The timing of these tests determines whether you are safe to continue to use heparin to help your doctor.

Dosage of Heparin

Heparin sodium is not effective with oral administration, and should be administered by intravenous injection, after dilution in 50 or 100 ml of a 5% injection of dextrose, USP or sodium chloride 0.9%, USP or intravenous injection.

The dose of heparin sodium should be adjusted according to the results of the patient's coagulation test. When heparin is given continuous intravenous infusion, the coagulation time should be determined approximately every 4 hours in the early stages of treatment. When the medicine is given intermittently by intravenous administration, coagulation tests are performed prior to each injection at the initial stages of treatment and at appropriate intervals thereafter. It is sufficient when the active component of the active thromboplastin (APTT) is 1.5 to 2 times normal or when the total blood clot time is about 2.5 to 3 times that of control.

Continuous infusion IV:

Primary dose: 5000 units IV

Maintenance dose: 20,000 to 40,000 units per 24 hours with continuous IV infusion

Injection IV:

Primary dose: 10,000 units IV

Maintenance dose: 5000 to 10,000 units IV every 4 to 6 hours

Symptoms of over dose 

Bleeding is the main sign of heparin transplantation. It may be bleeding, bleeding, or breathing stools. Small bruises or patches may include bruises, nosebleeds, blood in the urine or feces, black stools or blisters, or bleeding that may not stop before bleeding.


Please if you have any questions about Heparin, you can ask us by commenting below this text, we'll answer you as soon as possible.

Side effects of Heparin

Although unlikely, this medicine may bleed if its effect on your clotted proteins is too high. If any signs of severe bleeding, including unusual pain / swelling / discomfort, prolonged bleeding from the cuts or gums, acute hemorrhage, severe / prolonged menstruation periods, unusual / easy bruising, dark urine, faeces Black, severe headache, abnormal dizziness.

Some patients may have a poor response to heparin (heparin induced thrombocytopenia or HITT, and heparin induced thrombocytopenic hormone and HITT thrombosis). This can be stopped during treatment and up to several weeks after treatment with heparin.

If you have very serious side effects such as pain / loss of feeling in the hands / feet, change in the color of the arms / legs, chest pain, difficulty in breathing, confusion, weakness on one side of the body, rugged speech, visual changes. In the event that:

Any unusual bleeding or bruising

Severe pain in the stomach, back or groin;

Swelling or bleeding in the waist or groin area;

Nausea, vomiting, loss of appetite;

Unusual fatigue;

Any bleeding that will not stop

Other symptoms of bleeding, such as nose bleeding, blood in the urine or stool, black stool or blisters, or coughing up blood or vomiting, which appears to be like a coffee spot.

Heparin can cause you to bleed during use and several weeks after it is stopped.

Stop using heparin and contact your doctor if you have:

Signs of blood clotting - Insomnia or sudden weakness, severe headache, inconsistency, speech or vision problems, chest pain, sudden coughing, wheezing, swelling or heat in one or both legs.

Fever, chills, runny nose or runny nose

Breathing problem or

(In the baby) is severe sleepiness, weakness or breath.

Women over 60 may have more bleeding during heparin use.

Common side effects of heparin may include:

Mild pain, redness, heat, or skin changes in the medication;

Slight itching; legs; or

The skin is blue.

This list is not the full list of side effects and others may occur.

Drugs that may interact with Heparin

By using special medications with heparin, you can bleed more easily. This includes prescription and over-the-counter prescriptions, vitamins and herbal products. Tell your doctor about all your current medications and any medication you are taking or not taking.

This drug may interfere with certain laboratory tests (including prothrombin time), possibly resulting in spelling mistakes. Make sure your laboratory personnel and all your doctors know that you are using this medication.

Not all possible interactions are listed in this medication guide.

For whom Heparin might not be safe

Tell your doctor or pharmacist if you are allergic to heparin before taking heparin; or if you have pork products; or if you have an allergy. This product may contain inactive ingredients (such as benzyl alcohol in some brands) that can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Tell your doctor or pharmacist before taking this medicine.

Before surgery, tell your doctor or dentist about all the products you are using (including prescription drugs, over-the-counter prescriptions, and herbal medicines). You should not use this medication if you have allergies to heparin or pork medicines:

Severe platelet deficiency in your blood; or

Uncontrolled bleeding

To ensure heparin is safe for you, tell your doctor if you have any of these:

Your joint heart infection (also called bacterial endocarditis);

Uncontrolled hypertension;

A bleeding or blood clotting disorder;

A stomach or intestinal illness;

Liver disease;

If you use a nitrogen in your blood (warfarin, Coumadin) and you normally do "INR" or test the prothrombin time; or

If you have a period of menstruation.

It is unclear whether heparin will harm an unborn baby. Tell your doctor if you are pregnant.

The injection of heparin is not likely to be transmitted to breast milk, but if you have breast milk, you should tell your doctor.

Women over 60 may have more bleeding during heparin use.

Warnings of Heparin

This medication does not pass into breast milk. Consult your doctor before breast-feeding.


Please if you have any questions about Heparin, you can ask us by commenting below this text, we'll answer you as soon as possible.

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