What is Depression: Causes and Treatments

What is Depression: Causes and Treatments

What is depression?

Depression is a common pathology in Western countries. It affects 3% of men and 6% of women.

We may have the impression of knowing this disease without having ever been reached. The explanation is simple: among the wide range of emotions and sensations we experience in our lives, some are very painful. We hastily conclude that to be depressed is to feel more strongly and longer such sufferings. And that makes us believe that we can easily understand what a person with depression is going through.

Feeling sad, being "depressed", having "black thoughts" or experiencing sleep disturbances cannot be blown out of depression. For one to suffer from a major depressive disorder.

Please if you have any questions about Depression, you can ask us by commenting below this text, we'll answer you as soon as possible.

Depression can be caused by one or more factors, including biological, psychological, and environmental factors (related to the social or family environment).

Depression is a state of energy deprivation accompanied by a decline in neuropsychic tone and psychomotor retardation.

Its seriousness is related to the suicide death of its patients and the consequences of professional inactivity, whether temporary (sick leave) or permanent (disability), in this pathology that can potentially affect all individuals without predictive factors defined.

The depressions are considered according to various classifications, but, above all, according to their intensity.

Major depression is defined by daily signs persisting for more than 15 days, a rupture of the previous

Melancholy depression (or melancholy) is the most serious form of depression. It has a high risk of suicide and also a risk of undernutrition.

It can evolve into delirious forms requiring, if necessary, treatment by electro-convulsive therapy.

The depressive syndrome corresponds to the clinical picture that the person presents at the moment when he consults, but it is essential to place the various forms of depression in their context and in the patient's environment.

Impression of nervousness

For some people, depression makes them very restless and almost nervous (unable to sit, walk up and down, wring hands, fiddle with clothes or other items, etc).

Depressed sadness

The depressed mood suddenly imposes the throes of despair.

How do you recognize a depressed sadness?

The sadness of a depressed person has the following characteristics:

It is important to discuss any symptoms you present with your doctor.

Biological factors

We are not sure what causes depression. One of the main theories is that depression is caused by an imbalance of naturally occurring substances in the brain and spinal cord, known as neurotransmitters.

Serotonin and norepinephrine are two neurotransmitters in the brain that appear to play a role in the symptoms of depression.

Depression is not just a temporary change of mood or a sign of weakness. It is a real medical problem with many emotional, physical, behavioral and cognitive symptoms.

Psychological factors

People are affected by external events in a different way. Each person's thoughts determine what kind of life experience they will have, which may affect whether they will fall into depression or not.

Our way of thinking and perceiving the world is often established during childhood. For example, a strict education, in which critical and negative comments predominate, can shape the way we see things, and the strongest probability is that we perceive them negatively.

Therefore, it is not surprising that this way of thinking reinforces the negative effect of difficult situations in life, predisposing people to emotional suffering.

What is Depression

Please if you have any questions about Depression, you can ask us by commenting below this text, we'll answer you as soon as possible.

Environmental factors

Depression can often be triggered by very stressful life situations or by other factors, such as:

the death of a loved one, a move, a divorce, financial hardship or loss of employment;

social isolation;

periods of relationship conflict with a spouse or family;

demanding work or a stressful workplace;

health problems, especially when the person has a chronic health problem.

Sometimes the biggest hurdle to getting better and progressing is depression itself. For example, a depressed person often walks away from comforting and supportive loved ones or stops participating in activities of personal interest, which can contribute to his illness11.

Emotional symptoms

Permanent sadness, almost every day

This feeling of sadness can manifest itself for no apparent reason (as a serious event). It can be intense and nothing seems to make it disappear.

Sense of worthlessness, excessive guilt or inappropriate. A depressed person often experiences negative or unrealistic feelings of guilt.

Physical symptoms

People with depression often experience a decrease in energy, even if they have not exercised. This depressive fatigue is characterized by the fact that neither rest nor sleep attenuates it.

Behavioral symptoms

In most cases, the appetite diminishes: the food seems tasteless and the portions look too big. Conversely, people sometimes increase their consumption of food (especially sweets), which can lead to weight gain.

Psychomotor impairment

Depression can make you feel like your home is idling: slurred speech, thoughts, and body movements; longer breaks before answering; decreased volume and inflection of voice, quantity or variety of content. Muteism can also accompany depression.


Depression may be accompanied by physical pain (headache, joint pain, stomach pain or other pain)

Insomnia or, on the contrary, hypersomnia.

Sleep is often interrupted or not invigorating. The person often wakes up very early and the mental anguish prevents him from going back to sleep. Other cases may include excessive sleep.

Weight change

Often, weight loss or weight gain is an important sign for the diagnosis of depression.

Cognitive symptoms

Difficulty making decisions or concentrating.

Depression can diminish our ability to think or concentrate or can make us indecisive.

Treatment of Depression

The goal of any treatment is to help you become yourself again so that you can enjoy things as before. To do this, the right treatment to take care of and alleviate all your symptoms must be found. Even if you are prescribed medication, it may take some time and you may need to try different medications before you find the one that works best for you. In addition, the goal of treatment goes beyond improving your condition. You must continue to feel better.

Imipramine antidepressants, including clomipramine (Anafranil®), amitriptyline (Elavil®, Redomex®, Laroxyl®) and imipramine (Tofranil®), dosulpin (Prothiaden®), doxepin (Sinequan®, Quitaxon®) , maprotiline (Ludiomil®), nortriptyline (Nortrilen®). Used since the early 1960s, they caused a lot of side effects (drowsiness, weight gain, constipation, dry mouth, low libido, etc.). There is less recourse.

Selective serotonin reuptake inhibitors (SSRIs or serotonergic antidepressants), including citalopram (Celexa®, Seropram®), fluoxetine (Prozac®), fluvoxamine (Luvox®, Floxyfral®), paroxetine (Paxil®, Deroxat®, Divarius®) and sertraline (Zoloft®). This is usually the first choice of treatment for severe depression. Their effectiveness is equivalent to that of tricyclic antidepressants, but they are better tolerated. However, they can be associated with certain undesirable effects: agitation, nausea, nervousness, insomnia, headaches and loss of libido.

Inhibitors of the reuptake of serotonin and norepinephrine or noradrenaline (SNRI), such as venlafaxine (Effexor®), Duloxetine (Cymbalta®), Milnacipran hydrochloride (Ixel®). They are among the most effective antidepressants because they act on two types of neurotransmitters at a time. However, they can cause more side effects. Usually, they are used when other medications are insufficient to relieve symptoms.

In addition, a significant proportion of people with depression respond little or nothing to antidepressants. The psychiatrist can then prescribe 2 drugs of different classes simultaneously.

Sudden antidepressant therapy should never be discontinued, as it can lead to symptoms if it stops. The dose should be reduced gradually over a few weeks, following the advice of the doctor. That said, there are normally no dangerous withdrawal symptoms with antidepressants, only transient discomforts.

It is desirable, but not always essential, to wait a few days (or more, depending on the drug) before starting another pharmacological or natural treatment. Check with your doctor.

What is Depression

Please if you have any questions about Depression, you can ask us by commenting below this text, we'll answer you as soon as possible.

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