What is Seroquel: How to use, Side Effects, Dosage

What is Seroquel: How to use, Side Effects, Dosage

What is Seroquel

SEROQUEL® (quetiapine fumarate) is a psychotropic drug belonging to the derivative of dibenzothiazepine to a chemical class. All doses and strengths of the tablet are expressed as mg of base, not as salt of fumarate, its molecular formula is C42H50N6O4S2 • C4H4O4 and has a molecular weight of 883.11 (fumarate salt). Constructing formula:

SEROQUEL (quetiapine fumarate) Illustration Formula Structural

Quetiapine fumarate is a white or white crystalline powder that dissolves on average in water.

SEROQUEL is a 25 mg (round, peach), 50 mg (round, white), 100 mg (round, yellow), 200 mg (round, white), 300 mg (capsule, white) and 400 mg (capsule pill, yellow) tablets.

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How to use Seroquel?

Before you start using Seroquel and every time you refill, consult your doctor's guide and, if necessary, provide the patient information guide provided by your pharmacist. Ask your doctor or pharmacist if you have questions.

Take Seroquel in your mouth as prescribed by your doctor, usually 2 or 3 times a day with or without food. To treat depression with bipolar disorder, take this medicine as directed by your doctor, usually once a day during sleep.

The dose is based on your medical condition, the reaction to treatment and other medications that you may be taking. Make sure you tell your doctor and pharmacist about all the products you use (including prescription drugs, over-the-counter prescriptions, and herbal products).

To reduce the risk of side effects, your doctor may want to start taking this medicine at a low dose and gradually increase your dose. Follow your doctor's instructions carefully. Use this medication regularly to get the most out of it. To help you remember, take it every day at the same time.

Do not increase your dose or prescribe it more or more than your medicine. Your condition will not improve faster and the risk of your side effects increases.

It is important that you continue to take Seroquel even if you feel well. Do not stop taking medication without consulting your doctor. Some of these conditions may get worse if the drug suddenly stops. You may also experience symptoms such as low sleep, nausea, headaches, diarrhea, irritability. To reduce side effects, it should be gradually reduced. Report new or worse signs every time.


Seroquel is indicated for the treatment of schizophrenia. The efficacy of Seroquel in schizophrenia was developed in three 6-week-old adults and a six-week test in adolescents (17-17 years). The efficacy of Seroquel for the maintenance of schizophrenia has not been systematically evaluated in uncontrolled clinical trials (see clinical studies).

Dosage of Seroquel

Quick release Seroquel are usually taken twice or three times a day.

Seroquel is released once a day.

Usually the dose is slowly increased for several days or several weeks to achieve the desired effect.

Seroquel can be taken with or without food.

The initial dose for bipolar disorder is 50 mg twice daily (100 mg / day) free creatine. The dose can be increased by 100 mg per day to 400 mg per day. Most patients respond to 400 to 800 mg per day. Doses up to 800 mg per day have not been studied. The initial dose is 300 mg once a day and the target dose is 800 to 400 mg once a day when using long pills.

The initial dose of schizophrenia is 25 mg twice daily (50 mg per day) of immediate release pills. The dose can be increased by 25-50 mg twice or three times a day. The target dose is 300 to 400 mg per day in two or three doses. Patients respond to 150 to 750 mg per day, and do not exceed 800 mg per day. The initial dose is 300 mg once a day and the target dose is 800 to 400 mg once a day when using long pills.

The dose range for treating depression is important from 150 to 300 mg per day from long-term pills. Starting at 50 mg per night for 2 days increased to 150 mg per night.


Side effects of Seroquel

The most common side effects of Seroquel or Seroquel XR are

  • headache,
  • agitation,
  • dizziness,
  • drowsiness,
  • weight gain, and
  • And stomach upset.

Possible serious side effects include

  • suicidality,
  • worsening of depression,
  • extrapyramidal symptoms,
  • tarkive dyskinesia,
  • serious allergic reactions,
  • seizures,
  • stroke, and
  • Priapism.
  • Other important side effects contain a potentially fatal complex referred to as neuroleptic malignant syndrome (NMS), in which patients may have
  • high fevers,
  • muscle rigidity,
  • altered mental status,
  • irregular pulse or blood pressure,
  • rapid heart rate,
  • excessive sweating, and
  • Heart arrhythmias.
  • Quetiapine frequently causes tiredness (1 in 5 patients), especially during the first 3-5 days of treatment. Because of this tiredness, care should be exercised in any activity requiring mental alertness such as operating a motor vehicle or hazardous machinery.
  • Less common side effects include seizures (1 in 125 patients) and hypothyroidism (1 in 250 patients).

Seroquel while Pregnancy

Animal studies have shown evidence of embryo and fetal toxicity. Published human data does not report major constraints on use during pregnancy. There are no controlled data in human pregnancy. Infants exposed to antiviral drugs during the third trimester of pregnancy are at increased risk of overweight and / or postpartum withdrawal. It has been reported that excitement, hypotension, hypotension, tremor, drowsiness, respiratory distress and nutritional disorders have been reported in these infants. These complications vary in severity. While in some cases the symptoms are limited, in other cases, babies need care of the intensive care unit and long-term admissions. This medicine is recommended only for pregnancy, when there is no substitute and it has a higher risk.

Drugs that may interact with Seroquel

Common medications checked in combination with Seroquel (quetiapine)

  • Abilify (aripiprazole)
  • Adderall (amphetamine / dextroamphetamine)
  • amitriptyline
  • Ativan (lorazepam)
  • clonazepam
  • Cymbalta (duloxetine)
  • gabapentin
  • hydrocodone
  • Klonopin (clonazepam)
  • Lamictal (lamotrigine)
  • levothyroxine
  • Lexapro (escitalopram)
  • Lisinopril
  • metformin
  • Norco (acetaminophen / hydrocodone)
  • omeprazole
  • oxycodone
  • Percocet (acetaminophen / oxycodone)
  • Prozac (fluoxetine)
  • Remeron (mirtazapine)
  • Suboxone (buprenorphine / naloxone)
  • Synthroid (levothyroxine)
  • Topamax (topiramate)
  • tramadol
  • trazodone
  • Vicodin (acetaminophen / hydrocodone)
  • Vitamin D3 (cholecalciferol)
  • Xanax (alprazolam)
  • Zoloft (sertraline)

Seroquel (quetiapine) alcohol/food Interactions

There are 6 alcohol/food interactions with Seroquel (quetiapine)

Warnings of Seroquel

Before taking Seroquel, tell your doctor or pharmacist your doctor, in particular: eye cataracts, liver disease, white blood cell count (including the history of white blood cell count from medications), seizure disorder, swallowing problems , Thyroid problems, stomach and intestinal disorders (such as severe constipation, intestinal obstruction), stomach / intestines that are not moving (such as Jerome), personal or family history of diabetes, personal or family history of a substance abuse disorder (such as excessive consumption Limit or drug / alcohol dependence), heart disease, high blood pressure, high cholesterol / triglyceride levels, sleep disturbances (sleeping apnea), musk L urination (for example, due to enlarged prostate).

Seroquel may cause dizziness or drowsiness or disrupt your vision. Alcohol or marijuana can cause your dizziness or sleepiness. Do not drive, use machines, or do anything that requires calm or sight until you can safely do it. Avoid alcoholic beverages. Talk to your doctor if you use marijuana.

Quetiapine may cause a disease that affects the heart rhythm (QT prolongation). The duration of QT can rarely lead to serious / rash, and other symptoms (such as severe dizziness, choking), which can rarely lead to medical attention soon.

The risk of having a QT duration may increase if you have special medical conditions or other medications that may prolong QT. Before taking Seroquel, tell your doctor or pharmacist about all the medicines you are taking and have the following: Heart problems (heart failure, slow heart rate, QT duration in the EKG), family history of heart problems Specific (QT Lifespan in EKG, Sudden Death of the Heart).

Lower levels of potassium or magnesium in the blood may also increase your risk of developing QT. This risk may be increased by using certain medications (such as diuretics / water tablets) or if you have severe conditions such as diarrhea or vomiting. Speak safely with your doctor about using Seroquel.


Please if you have any questions about Seroquel, you can ask us by commenting below this text, we'll answer you as soon as possible.

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