What is Zytiga: Side Effects, Dosage, How to use

What is Zytiga: Side Effects, Dosage, How to use

What is Zytiga?

ZYTIGA (abiraterone acetate) is an inhibitor of CYP17 (17a-hydroxylase/C17,20-lyase) is a prescription medicine that is used along with prednisone. ZYTIGA is used to treat men with prostate cancer that has spread to other parts of the body. It also reduces the levels of the sex hormone testosterone.

Zytiga (abiraterone) works by reducing androgen production in the body. Androgens are male hormones that can promote tumor growth in the prostate gland.

This medication is mainly used together with steroid medication (prednisone or methylprednisolone) to treat prostate cancer that has spread to other parts of the body.

Zytiga is used in men whose prostate cancer cannot be treated with surgery or other medicines.

You might have abiraterone if:

other hormone treatments are no longer working

you have had docetaxel chemotherapy

You might also have abiraterone as part of a clinical trial for early stage prostate cancer.

Also know that this medication should not be given to women or children.

Please if you have any questions about Zytiga, you can ask us by commenting below this text, we'll answer you as soon as possible.

How to use Zytiga?

Take ZYTIGA and prednisone exactly as your healthcare provider tells you.

Take your prescribed dose of ZYTIGA 1 time a day.

Your healthcare provider may change your dose if needed.

Do not stop taking your prescribed dose of ZYTIGA or prednisone without talking with your healthcare provider first.

Take ZYTIGA on an empty stomach, either one hour before or two hours after a meal. Do not take ZYTIGA with food. Taking ZYTIGA with food may cause more of the medicine to be absorbed by the body than is needed and this may cause side effects.

Swallow ZYTIGA tablets whole. Do not crush or chew tablets

Take ZYTIGA tablets with water.

Men who are sexually active with a pregnant woman must use a condom during and for 3 weeks after treatment with ZYTIGA. If their female partner may become pregnant, a condom and another form of birth control must be used during and for 3 weeks after treatment with ZYTIGA. Talk with your healthcare provider if you have questions about birth control.

If you miss a dose of ZYTIGA or prednisone, take your prescribed dose the following day. If you miss more than 1 dose, tell your healthcare provider right away.

Your healthcare provider will do blood tests to check for side effects.

Side effects of Zytiga

Like other drugs Zytiga has some various unwanted effects that must be cared by the patients and be informed to the doctor right away they are seen or not they may lead to other serious problems. Here is a list of these side effects:

Call your doctor at once if you have:

swelling in your ankles or feet, pain in your legs;

shortness of breath;

pain or burning when you urinate, blood in your urine;

fast heartbeats;

headache, confusion;

a light-headed feeling, like you might pass out;

muscle weakness; or

liver problems - stomach pain (upper right side), nausea, vomiting, dark urine, jaundice (yellowing of the skin or eyes).

Common side effects

indigestion, vomiting, diarrhea, constipation;

painful or difficult urination;

swelling in your legs or feet;

feeling weak, feeling very hot;

muscle pain;

abnormal blood tests;

joint pain or swelling;

bruising; or

cold symptoms such as stuffy nose, sneezing, cough, sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

Zytiga

Please if you have any questions about Zytiga, you can ask us by commenting below this text, we'll answer you as soon as possible.

Warnings of Zytiga

Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart problems (such as heart failure, irregular heartbeat, previous heart attack), high blood pressure, liver problems.

This medication should not be used in women, especially during pregnancy or breast-feeding. It may harm an unborn or breast-feeding baby. Women who are pregnant or breast-feeding should avoid touching or accidentally taking this medication. Consult your doctor for more details.

Using corticosteroid medications for a long time along with abiraterone can make it more difficult for your body to respond to physical stress. Therefore, before having surgery or emergency treatment, or if you get a serious illness/injury, tell your doctor or dentist that you are using this medication or have used this medication within the past 12 months. Tell your doctor right away if you develop unusual/extreme tiredness or weight loss. If you will be using this medication for a long time, carry a warning card or medical ID bracelet that identifies your use of this medication. Because it is unknown if abiraterone passes into semen, men who use this drug and have sex with pregnant women must use a latex condom during all sexual contact, even if they have had a vasectomy. Men who use this drug and have sex with women of child-bearing age should use a latex condom and another reliable form of birth control (such as diaphragm with spermicide) during all sexual contact. Continue using reliable form(s) of birth control as directed until 3 weeks after abiraterone treatment has been stopped.

Before taking abiraterone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Drugs that may interact with Zytiga

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions.

Here is a list of Common medications checked in combination with Zytiga (abiraterone)

amlodipine (Norvasc)

aspirin (Aspir 81, Ecotrin, Acetylsalicylic Acid, Aspirin Low Strength, Bayer Aspirin, Aspir-Low, Ascriptin, Arthritis Pain, Fasprin, Ecotrin Adult Low Strength, Low Dose ASA, Bufferin, Aspiritab, Aspirin Lite Coat, Easprin, Bayer Children's Aspirin, St. Joseph 81 mg Aspirin Enteric Safety-Coated, Bayer Aspirin Regimen, Aspirtab, Halfprin, Aspergum, Durlaza, Acuprin 81, Miniprin, Bufferin Low Dose, Empirin, Buffered Aspirin, Entercote, St. Joseph Aspirin, Ascriptin Enteric, Ecpirin, Bayer Women's Aspirin With Calcium, Ascriptin Maximum Strength, Arthritis Foundation Pain Reliever, Bayer Aspirin with Heart Advantage, Aspi-Cor, Medi-Seltzer, Sloprin, St. Joseph 81 mg Chewable Aspirin, ZORprin, Bayer Aspirin Extra Strength Plus, Buffex, Ecotrin Maximum Strength, Extra Strength Bayer, Genacote, Gennin-FC, Genprin, Litecoat Aspirin, Minitabs, Tri-Buffered Aspirin, Entaprin, Bufferin Arthritis Strength, Bufferin Extra Strength, Therapy Bayer, Stanback Analgesic, Norwich Aspirin, Zero-Order Release, YSP Aspirin, Migralex, Heartline, Bayer Advanced Aspirin, Buffasal)

atorvastatin (Lipitor)

bicalutamide (Casodex)

Calcium 600 D (calcium / vitamin d)

Casodex (bicalutamide)

Crestor (rosuvastatin)

dexamethasone (Decadron, Dexamethasone Intensol, Dexasone, Hexadrol, Decadron Phosphate, Injectable, Zonacort, Decadron-LA, Dexacen-4, LoCort, Adrenocot LA, TaperDex, Dalalone, Dalalone DP, Dalalone LA, Decaject, Decaject LA, Zema Pak, Baycadron, Dexacort Phosphate in Respihaler, Solurex LA, Solurex, Adrenocot, De-Sone LA, Dexacort-LA, Dexasone LA, Dexone, Dexone LA, Primethasone, ZoDex, Dexacorten, Medidex, Medidex LA, Dexpak Taperpak)

furosemide (Lasix, Diaqua-2, Lo-Aqua)

gabapentin (Neurontin, Gralise, Gabarone, Fanatrex)

lisinopril (Zestril, Prinivil, Qbrelis)

Lupron (leuprolide)

Lupron Depot (leuprolide)

metformin (Glucophage, Glumetza, Glucophage XR, Riomet, Fortamet)

omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)

oxycodone (OxyContin, Roxicodone, Xtampza ER, OxyIR, Oxaydo, Percolone, Oxyfast, RoxyBond, Dazidox, Oxecta, Roxicodone Intensol, Oxydose, M-Oxy, ETH-Oxydose, Endocodone)

OxyContin (oxycodone)

prednisone (Deltasone, Rayos, Sterapred DS, Sterapred, Prednicot, Meticorten, Liquid Pred, Orasone, Prednicen-M)

simvastatin (Zocor, FloLipid)

tamsulosin (Flomax)

Taxotere (docetaxel)

Vitamin D3 (cholecalciferol)

warfarin (Coumadin, Jantoven)

Xgeva (denosumab)

Xtandi (enzalutamide)

Dosage of Zytiga

Usual Adult Dose for Prostate Cancer:

1,000 mg orally once a day on an empty stomach (in combination with prednisone 5 mg orally 2 times a day)

Comments: No food should be consumed for at least 2 hours before the dose and for at least 1 hour after the dose of this drug.

Skip the missed dose and take the medicine the following day. Do not take two doses at one time.

Call your doctor for instructions if you miss more than one dose of Zytiga.

Zytiga

Please if you have any questions about Zytiga, you can ask us by commenting below this text, we'll answer you as soon as possible.

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