What is Buspirone: How to Use, Side Effects, Dosage, Warnings

What is Buspirone: How to Use, Side Effects, Dosage, Warnings

What is Buspirone

Buspirone is an anti-anxiety drug that affects chemicals in the brain that may be unbalanced in people with anxiety.

Buspirone is not an anti-psychotic medication and should not be used in place of medication prescribed by your doctor for mental illness.

Buspirone is used to treat symptoms of anxiety, such as fear, tension, irritability, dizziness, pounding heartbeat, and other physical problems.

This medication may help you think more clearly, relax, worry less, and take part in everyday life. It may also help you to feel less jittery and irritable, and may control symptoms such as trouble sleeping, sweating, and pounding heartbeat. Buspirone is a medication for anxiety (anxiolytic) that works by affecting certain natural substances in the brain (neurotransmitters).

Please if you have any questions about Buspirone, you can ask us by commenting below this text, we'll answer you as soon as possible.

How to use Buspirone

Take buspirone exactly as it was prescribed for you by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results from your treatment. Do not take this medicine in larger or smaller amounts or for longer than suggested.

Some buspirone tablets are scored so you can break the tablet into 2 or 3 pieces in order to take a smaller amount of the medicine at each dose. Do not use a tablet if it has not been broken correctly and the piece is too big or too small.

If you have switched to buspirone from another anxiety drug, you may need to slowly decrease your dose of the other medication rather than stopping suddenly

This medication can cause false positive results with certain medical tests. You may need to stop using the medicine for at least 48 hours before your test. Tell any doctor who cures you that you are using buspirone.

Take this medication by mouth, usually 2 or 3 times a day or as directed by your doctor. You may take this medication with or without food, but it is important to choose one way and always take it the same way so that the amount of drug absorbed will always be the same.

Buspirone may come in a tablet that can be split to get the correct dose for you. 

Dosage of Buspirone

Initial dose: 7.5 mg orally two times a day or 5 mg 3 times a day.

Maintenance dose: The daily dose may be increased in 5 mg increments every 2 to 3 days up to 20 to 60 mg/day in divided doses.

Maximum dose: 60 mg per day

Usual Pediatric Dose for Anxiety:

6 to 18 years:

Initial dose: 2.5 to 10 mg daily.

Maintenance dose: The daily dose might be increased in 2.5 mg increments every 2 to 3 days to 15 to 60 mg/day given in 2 divided doses.

Study (n=26) Anxiety and Moderately Severe Aggression:

5 to 15 years: 5 mg daily, titrated upwards every 3 days by 5 to 10 mg, to a maximum of 50 mg daily dose.

Study (n=22) Anxiety and Irritability in Children with Pervasive Developmental Disorders:

6 to 17 years: 5 mg three times daily, titrated to a maximum of 45 mg/day within 3 weeks.

The recommended initial dose is 15 mg daily (7.5 mg b.i.d.). To achieve an optimal therapeutic response, at intervals of 2 to 3 days the dosage may be increased 5 mg per day, as needed. The maximum daily dosage should not exceed 60 mg per day. In clinical trials allowing dose titration, divided doses of 20 mg to 30 mg per day were commonly employed.

Buspirone

Please if you have any questions about Buspirone, you can ask us by commenting below this text, we'll answer you as soon as possible.

Side effects of Buspirone

Get emergency medical help if you have any signs of an allergic respond to buspirone: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

chest pain;

shortness of breath; or

a light-headed feeling, like you might pass out.

Common buspirone side effects may include:

headache;

dizziness, drowsiness;

sleep problems (insomnia);

nausea, upset stomach; or

feeling nervous or excited.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Drugs that may interact with Buspirone

Taking this medicine with other drugs that make you sleepy or slow your breathing can worsen these effects. Ask your doctor before taking buspirone with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.

Other drugs may interact with buspirone, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines that you use now and any medicine you start or stop using.

Using Buspirone while pregnancy

This drug must be used during pregnancy only if clearly needed.

AU TGA pregnancy category: B1

US FDA pregnancy category: B

Animal studies have not revealed any fetal damage or fertility impairment. There are no controlled information in human pregnancy.

AU TGA pregnancy category B1: Drugs that have been taken by only a limited number of pregnant women and women of childbearing age, without an increase in the frequency of malformation or other direct or indirect harmful effects on the human fetus having been observed. Studies in animals have not shown evidence of an increased occurrence of fetal damage.

US FDA pregnancy category B: Animal reproduction studies have been failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.

Warnings of Buspirone

Before taking buspirone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more information.

This medication should not be used if you have certain medical conditions. Before using this medication, consult your doctor if you have: kidney problems, liver problems.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: bipolar disorder (manic-depression), Parkinson's disease.

This drug may make you dizzy or drowsy. Alcohol or marijuana can make you more dizy or drowsy. Do not drive, use machinery, or do anything that may need alertness until you can do it safely. Avoid alcoholic beverages. Talk to your doctor if you are using marijuana.

If you are taking other medications for anxiety, do not suddenly stop them unless suggested by your doctor. Buspirone will not prevent withdrawal symptoms from other medications, and your dose may need to be lowered slowly when you switch to buspirone. Discuss your treatment plan with your doctor. If you experience withdrawal symptoms, tell your doctor right away.

Mental alertness warning: You’re at increased risk of being drowsy and less alert while taking buspirone. Use caution while driving a car or using machinery until you know how this medication affects you.

Benzodiazepine withdrawal reactions warning: If you’ve been taking a benzodiazepine drug (such as clonazepam, alprazolam, or lorazepam) for anxiety long term (a month or longer), talk with your doctor. They will likely have you slowly stop taking the benzodiazepine drug before you start taking buspirone. Or, your doctor may slowly decrease your dosage of the benzodiazepine while increasing your dosage of buspirone over several weeks. If your current benzodiazepine medication is stopped suddenly and replaced with buspirone, you may have withdrawal reactions. These may include feeling irritable or nervous, trouble sleeping, tremor, cramps, vomiting, sweating, or flu-like symptoms.

Delayed effect warning: When taking this drug, you may see a decrease in your anxiety within 2 weeks. However, you likely won’t see the full effect of the drug until 3–6 weeks after you start taking the drug.

Buspirone

Please if you have any questions about Buspirone, you can ask us by commenting below this text, we'll answer you as soon as possible.

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