What is Atripla: How to Use, Dosage, Side Effects, Warnings

What is Atripla: How to Use, Dosage, Side Effects, Warnings

What is Atripla

Atripla for the treatment of HIV is a virus that can cause immunodeficiency syndrome (AIDS). This drug is not a treatment for HIV and AIDS.

Atripla contains a combination of efavirenz, emtricitabine, and tenofovir. Efavirenz, emtricitabine and antiviral drugs that prevent your immune deficiency (HIV virus) from reproducing in your body. Efavirenz belongs to a class of drugs known as reverse transcriptase inhibitors (NNRTIs). Emtricitabine and tenofovir belong to a group of drugs known as reverse transcriptase inhibitors (NRTIs).

Atripla is for use in adults and children at least 12 years old and weighs at least 88 pounds (40 kilograms).

This product has three different drugs: efavirenz, emtricitabine and tenofovir. It is used alone or with other viral drugs to control HIV infection. It helps reduce the amount of HIV in your body so your immune system can work better. This reduces the risk of developing an HIV infection (such as new infections, cancer) and improves your quality of life.

 

 

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How to use Atripla

You need to have more frequent medical tests.

Use this drug with a full glass of water.

This drug may affect your urine screening medication and you may have a false outcome. Tell the lab staff that you are taking efavirenz, emtricitabine and tenofovir. Since this product is a combination of fixed doses of efavirenz, emtricitabine, and tenofovir, you should use it if you have been told by your doctor that the dose of all the medications in this product is right for you.

Take this medication in your mouth on an empty stomach, without food, usually once a day before bedtime or as directed by your doctor. Taking this medicine at bedtime reduces some of the side effects.

 

 

Dosage of Atripla

Recommended Dosage for Adults and Pediatric Patients Weighing at Least 40 kg

ATRIPLA is a three-drug fixed-dose combination product containing 600 mg of efavirenz (EFV), 200 mg of emtricitabine (FTC), and 300 mg of tenofovir disoproxil fumarate (TDF). The recommended dosage of ATRIPLA in adults and pediatric patients weighing at least 40 kg is one tablet once daily taken orally on an empty stomach. Dosing at bedtime may improve the tolerability of nervous system symptoms.

ATRIPLA is not recommended in patients with moderate or severe renal impairment (estimated creatinine clearance below 50 mL/min).

ATRIPLA is not recommended in patients with moderate to severe hepatic impairment (Child Pugh B or C).

 

Dosage Adjustment with Rifampin

If ATRIPLA is co-administered with rifampin in patients weighing 50 kg or more, take one tablet of ATRIPLA once daily followed by one additional 200 mg per day of efavirenz.

 

Symptoms of over dose 

If excessive administration occurs, the patient should be monitored for evidence of toxicity and, if necessary, standard supportive treatment is applied. The use of active activated charcoal can be used to help remove non-absorbed EFV. Hemodialysis can remove both the FTC and the TDF, but it is unlikely to remove EFV from blood.

 

 

Atripla

 

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Side effects of Atripla

Common colds, drowsiness, low sleep, unusual dreams, and overcoming problems often occur. Side effects may start 1-2 days after starting the drug and usually disappear within 2 to 4 weeks. They are also reduced by taking this medication in the empty stomach during sleep.

Rarely, this drug can cause severe (sometimes fatal) liver and blood (lactic acidosis). If you have symptoms of liver problems (such as nausea / vomiting that does not stop, loss of appetite, stomach or stomach ache, yellow / eyes / skin, dark urine) or lactic acidosis (such as deep / fasting breathing, sleepiness, nausea / vomiting), Unusual weakness).

 

Drugs that may interact with Atripla

Do not use Atripla together with atazanavir, adefovir, voriconazole, or drugs that contain emtricitabine, lamivudine, or tenofovir.

Do not take Atripla with Adefovir, Atazanavir, Voriconazole or any drug containing emtricitabine, lamivudine or tenofovir (such as Combivir, Descovy, Complera, Epivir, Epzicom, Genvoya, Odefsey, Stribild, Trizivir, Truvada, Vemlidy).

 

Tell your doctor if you are sure that Atripla is safe for you, while you have these symptoms:

Liver or kidney disease;

Long QT syndrome;

Hepatitis B or C infection.

Mental illness, use of antipyretic drugs or injecting drugs;

Epilepsy or other seizure disorders;

Low bone mineral density; or

You may develop lactic acidosis, a dangerous buildup of lactic acid in your blood. This may be greater if you have other medical conditions, if you have taken medicines for a long time or if you are a woman. Ask your doctor about your risk.

 

 

For whom this drug might not be safe

Elderly adults may be more susceptible to side effects, especially QT prolongation.

This medicine is transmitted to breast milk. Since breast milk can transmit HIV, do not feed it.

 

 

Can you use Atripla while pregnancy?

Efavirenz, emtricitabine and tenofovir can cause congenital defects. Do not use Atripla if you are pregnant and do not become pregnant for at least 12 weeks after taking this medicine.

Atripla can lower the hormonal birth control (control, control, injection, implants, skin patches, vaginal rings). To prevent pregnancy, use two types of contraceptive precautions (condom or aperture with spermicide).

During pregnancy, this drug should only be used when needed. Treatment can reduce the risk of HIV infection to your baby, and Infovarence / Amtrizeptine / Tonfuvir may be part of this treatment. Talk with them about the dangers and benefits of the doctor.

 

 

Warnings of Atripla

Before using this medication, check with your doctor or pharmacist about your medical history, especially kidney problems, liver problems (such as hepatitis B or C, cirrhosis), mental / mental conditions (such as depression, suicidal thoughts, psychotherapy), medication / Drugs / alcohol consumption, seizure, high cholesterol / triglyceride levels, bone problems (such as bone disease, bone loss / osteoporosis, bone fracture / fracture), pancreatitis (pancreatitis).

Efavirenz / emtricitabine / tenofovir may cause an illness that affects the cardiac rhythm (prolongation QT). Long QT can rarely cause severe (rarely fatal) rapid / irregular heartbeat and other symptoms (such as severe dizziness, fainting) that require medical attention right away.

Do not take medications from the toilet or drain them unless ordered to do so. After completing it, you will no longer need this product. Consult your local pharmacy or local waste disposal company.

 

Atripla

 

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