Enalapril: How to use, Side Effects, Dosage

Enalapril: How to use, Side Effects, Dosage

What is Enalapril?

Enalapril is an ACE inhibitor. ACE stands for angiotensin converting enzyme. Enalapril is used to treat high blood pressure (hypertension) in adults and children who are at least 1 month old. Enalapril is also used to treat congestive heart failure in adults.

Enalapril is a medicine used to treat high blood pressure. This is a class of drugs that use enzyme-linked enzyme (ACE) enzymes. ACE is an enzyme in the body that causes angiotensin II to form. Angiotensin II causes the arteries to narrow in the body, so blood pressure rises. ACE inhibitors, such as enalapril, lower blood pressure by preventing the formation of angiotensin II to relax the arteries. ACE inhibitors also improve cardiac efficacy in patients with heart failure by reducing blood pressure that the heart needs to maintain.

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How to use Enalapril?

Take enalapril either orally or without food, usually once a day or as your doctor. If you leave enalapril too long, you may need to wake up. Therefore, it is best to bring enalapril at least 4 hours before bedtime. Ask your doctor or pharmacist if you have questions about your dose schedule.

If you also have cholestyamine or cholestypole, you should take Enalapril / Hydrochlorothiazide 4 hours or at least 4 to 6 hours after each of these medications.

The dosage is based on your medical condition and response to treatment.

Use enalapril regularly to benefit more from it. To help you remember, put it at a time every day.

It may take a few weeks to get the full benefits of enalapril. It is important to continue taking enalapril even if you feel well. Most people with high blood pressure do not feel sick.

If your condition does not heal or worsen (eg, your usual blood pressure reading will be or will increase), tell your doctor.

Dosage of Enalapril

The usual oral dose for treating high blood pressure is 2.5-40 mg once daily. It may also be administered twice daily in two divided doses. The dose for treating heart failure is 2.5-20 mg given twice daily. The usual starting intravenous dose is 1.25 mg administered over a 5minute period every 6 hours. If a patient is receiving diuretic therapy the initial intravenous dose is 0.625 mg every 6 hours.

Enalapril Overdose

Limited data are available in relation to overdose in humans.

Oral doses of enalapril above 1000 mg / kg and 1,775 mg / kg were found in mice and rats, respectively.

The most common overdose is hypotension, which is the usual treatment of normal intravenous infusion of normal saline.

Through hemodialysis, enalaprilat may be eliminated through general bleeding and through the hemorrhage of neonates through peritoneal wall

Enalapril while Pregnancy

Animal studies have revealed evidence of fetotoxicity. In humans, use of drugs that act on RAS during the second and third trimesters can cause the following: reduced fetal renal function leading to anuria and renal failure, oligohydramnios, fetal lung hypoplasia and skeletal deformations including skull hypoplasia, hypotension, and death. There are no controlled data in human pregnancy.

Side effects of Enalapril

Along with its needed effects, enalapril may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking enalapril:

  • Blurred vision
  • confusion
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • sweating
  • unusual tiredness or weakness
  • Chest pain
  • cough producing mucus
  • diarrhea
  • difficult or labored breathing
  • fainting
  • fever or chills
  • nausea
  • sneezing
  • sore throat
  • tightness in the chest
  • vomiting

Some side effects of enalapril may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

  • Dizziness
  • Lack or loss of strength
  • rash

EnalaprilPlease if you have any questions about Enalapril, you can ask us by commenting below this text, we'll answer you as soon as possible.

Drugs that may interact with Enalapril

Common medications checked in combination with enalapril:

  • Acetylsalicylic Acid (aspirin)
  • Advil (ibuprofen)
  • Aleve (naproxen)
  • amlodipine
  • Aspir 81 (aspirin)
  • aspirin
  • Aspirin Low Strength (aspirin)
  • atenolol
  • Benadryl (diphenhydramine)
  • Crestor (rosuvastatin)
  • Cymbalta (duloxetine)
  • Fish Oil (omega-3 polyunsaturated fatty acids)
  • furosemide
  • hydrochlorothiazide
  • ibuprofen
  • Lantus (insulin glargine)
  • Lasix (furosemide)
  • Lipitor (atorvastatin)
  • Lisinopril
  • Lyrica (pregabalin)
  • metoprolol
  • Metoprolol Succinate ER (metoprolol)
  • Metoprolol Tartrate (metoprolol)
  • Nexium (esomeprazole)
  • Paracetamol (acetaminophen)
  • Plavix (clopidogrel)
  • Synthroid (levothyroxine)
  • Tylenol (acetaminophen)
  • Viagra (sildenafil)
  • Vitamin B12 (cyanocobalamin)
  • Vitamin C (ascorbic acid)
  • Vitamin D3 (cholecalciferol)

Warnings of Enalapril

Tell your doctor or pharmacist before taking this product, if you are allergic to enalapril or hydrochlorothiazide, or to other ACE inhibitors (such as captopril, lisinopril), or to other thiazides (such as chloroticase); or if you have an allergy. This product may contain inactive material that can cause allergic reactions and other problems. Talk to your pharmacist for more information.

If you have special medical conditions, enalapril should not be used. Before using enalapril, consult your doctor or pharmacist if you have: A history of an allergic reaction including swollen face / lip / tongue / throat (angioedema), urinary incontinence (anorexia).

Before using enalapril, your doctor or pharmacist, especially with regard to kidney disease (such as renal artery stenosis), liver disease, lupus, gout, salt imbalance without treatment (such as high calcium, high or low potassium, low magnesium), Excessive loss of water (dehydration), blood filtering methods (such as LDL depression, dialysis).

Enalapril may cause you dizziness. Alcohol or marijuana causes dizziness. Do not drive, use machines, or do anything that you need to be alert to as long as you can safely do it. Limit alcohol drinks. Talk to your doctor if you use marijuana.

To reduce the risk of dizziness and dizziness, get up slowly when rising from sitting or lie.

To help prevent dizziness, drink plenty of fluids when using enalapril, unless your doctor has instructed you to do this in an indirect way. Sweating, diarrhea, or vomiting may cause dizziness. Report long-term diarrhea or vomiting to your doctor.

Before your surgery, tell your doctor or dentist that you are taking enalapril.

Enalapril may make you more sensitive to the sun. Limit your time in the sun. Avoid tanning booths and solar bulbs. Use sunscreen and remove protective clothing. Tell your doctor if you have sunburns or red / red caviar skin.

This product may affect your potassium level. Consult your doctor or pharmacist before using potassium supplements or potassium-containing salt substitutes.

If you have diabetes, this product may affect your blood glucose. Check your blood glucose regularly and share your results with your doctor. Tell your doctor if you have signs of high blood sugar such as thirst / urine or signs of low blood sugar such as sweating, shaking, fast heartbeat, hunger, blurred vision, dizziness, or burning of your hands / feet. Your doctor may need to adjust your diabetes medication, exercise program, or diet.

Elderly adults may be more sensitive to the side effects of enalapril, especially dizziness and changes in urine (renal problems).

Enalapril is not recommended for use during pregnancy because the risk of developing a baby is not born. Consult your doctor for details. 

This product is transmitted to the mother's milk, but it is unlikely that the baby is sweet. Consult your doctor before breast-feeding.


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